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Mosadegh Jabbari, Shahrzad Ossareh, Ahad J. Ghods. Nephrology Department, Iran University of Medical Sciences, Tehran, Iran During the past decade the immunosuppressive therapy and the treatment of post transplant Tx ; infections has greatly improved. As a result the cardiovascular disease CVD ; is gradually emerging as the leading cause of death and graft loss in Tx recipients. Between April 1986 and April 1999, 1239 renal Tx have been performed in our center. The aim of this study was to investigate the prevalence of CVD and its major risk factors in our Tx recipients. Nine hundred eighteen renal Tx recipients who fulfilled our follow-up criteria were included in this study. 573 were male and 345 female. The mean age was 34 11 years and the mean post Tx follow-up period was 56 39 months. During the follow-up period a total of 65 renal Tx recipients developed CVD 7.1% ; and 33 of them died 50.7% ; . Of these 65 patients, 55 were male and 10 female. The type of CVD was acute myocardial infarction in 47, angina pectoris in 12 and cerebrovascular accident in 6 patients. When 65 Tx recipients with CVD were compared with 853 Tx recipients who apparently had no CVD, the male sex 84.6% vs. 60.7%, p 0.0001 ; and the older age 448 vs. 3310, p 0.0005 ; were major risk factors for CVD in renal Tx recipients. Hypertension 50.8% vs. 23.7% p 0.0003 ; and diabetes 9.2% vs. 0.9%, p 0.0001 ; were also found to be significant risk factors for CVD!

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Alternative medicine. Expanding medical horizons: A report to the National Institutes of Health on alternative medical systems and practices in the United States. Washington DC ; : Government Printing Office; 1994. Canadian Medical Association. A patient's guide to choosing unconventional therapies. Can Med Assoc J 1998; 158: 1161-1165. Cant S, Sharma U. Complementary and alternative mediums: Knowledge in practice. London: Free Association Press; 1996. Dillard J, Ziporyn T. Alternative medicine for dummies. New York: IDC Books Worldwide; 1998. McGuinness H. Holistic Therapies. Hodder & Stoughton; 2000. Oppel L. Protecting patients against "quackery." Can Fam Phys 1998; 44: 487-488. Ramsay C, Walker M, Alexander J. Alternative medicine in Canada: Use and public attitudes. Public Policy Sources. Fraser Institute; 1999. Verhoef MJ. Complementary medicine: Impact on physicians. Paper presented at the Insight Information Symposium; Nov 1998; Toronto, Ontario. Wilson E, Lewith G. Natural Born Healers. Collins & Brown Ltd; 1997 and stimate.
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'This work was supported by the Clinical and Biochemical Pharma cology Grant GM16538-05, USPHS General Medical Sciences ; , and the Clinical Pharmacology-Immunology Cancer Research Center Grant I-PO2-CA-13943-01 CAP. Received October 5, 1973; accepted December 11, 1973 and tolterodine.

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